We are pleased to report the first publication related to SPiQE in Clinical Neurophysiology (July 2019 edition). It is entitled ‘SPiQE: An automated analytical tool for detecting and characterising fasciculations in amyotrophic lateral sclerosis’. You can access it here as an Open Access article.


A follow-up article, entitled ‘Preprocessing surface EMG data removes voluntary muscle activity and enhances SPiQE fasciculation analysis’, became available in November 2019. You can access is here as an Open Access article.


Most recently, we have published several papers focusing on specific clinical questions in ALS. All are available as Open Access articles:


Fasciculations demonstrate daytime consistency in amyotrophic lateral sclerosis


The rise and fall of fasciculations in amyotrophic lateral sclerosis


The evolving role of surface electromyography in amyotrophic lateral sclerosis


SPiQE was also used to assess fasciculation counts in the description of two cases with benign fasciculation syndrome. You can access it here.


Results from the project have been presented at several recent international conferences, including the International MND Association Symposium (Perth, Australia, December 2019), the American Association of Neuromuscular and Electrodiagnostic Medicine annual meeting (Austin, Texas, USA, October 2019) and the European Network for the Cure of ALS conference (Tours, France, May 2019).

We have also presented updates of our work more locally, with James Bashford being named as winner of the ‘Best Departmental Talk’ at the King’s College London Neuroscience PhD Symposium (May 2019) .


In May 2020, James Bashford presented on online webinar as part of TMSi’s ‘Expert Talks’ series. This is entitled ‘Detecting motor unit pathophysiology in ALS using high-density surface EMG’ and provides a summary of our research group’s results so far. The webinar can be viewed here.