We are delighted to announce the launch of our new website: https://spiqe.co.uk


SPiQE represents a collaborative project between two of London’s top universities. Bringing together clinical expertise in the field of neurology from King’s and expert bioengineering knowledge of signal processing from Imperial, SPiQE aims to tackle some of neuroscience’s unanswered questions.


With a particular focus on the incurable neurodegenerative disorder motor neuron disease (also known as ALS), our non-invasive surface electrode technology detects involuntary muscle twitches in patients with the disease. By taking multiple snapshots over the course of a year, our goal is to learn more about the way motor neurons degenerate and ultimately develop a new tool to track disease progression. This is something that the field sorely lacks, as it would enable a more accurate way to detect the effectiveness of potential new therapies in clinical trials.


We have developed an automated method of analysis improving the objectivity and reliability of the results. We have completed our core longitudinal study of 25 patients, where assessments took place every two months for one year. We will report on these findings during 2019/2020.


Until then, please become acquainted with this new technique by looking through our ‘science’ and ‘clinical trials’ pages. We believe it has the power to help answer many key questions about fasciculations in motor neuron disease.

Leave a reply